I did a closing for this building a while back starting as Antonio's Restaurant and going through a number of different nightclubs and strip clubs.
At the time I made that post, the building seemed to be operating as Club Ego (despite the Studio 54 sign still being up). Since that time, Club Ego apparently shut down, and Club Colorz opened and shut.
I'm putting the closing date for Club Colorz as December 2010 because the flyers posted by the door talk about Christmas events (though I am not nearly hip enough to understand the contests being described), but not New Years events.
The building still has power, and is lighted nightly, so I presume there will be a new club by and by.
UPDATE 4 September 2011 -- It's now Laguna Sports Bar: