Rish Florist (aka Rish Flower Shop) is on that little strip of State Street in West Columbia that also houses Terra and The New Bookland Tavern. They appear to have expanded out of their original space over the years to take what looks like three different storefronts. I really like the Depression-era glass blocks in parts of the building.
The closing sign says that they had been there for 57 years -- that is certainly a record that anyone could be proud of.
(Hat tip to commenter JB)
UPDATE 20 September 2012 -- Well, somebody apparently has a plan for this building. The interior has been gutted, and there is some sort of zoning hearing scheduled: