Julie's was a small Columbia restaurant chain with a Bennigans-like concept. There were two in town, one on the frontage road at the Broad River Road/I-20 interchange, and one on Garner's Ferry Road near the old Woodhill Mall (about where Hampton Hills Athletic Club is now, but closer to the road).
I think these two started in the heyday of restaurants like Bennigans and Tuesdays 1865 (though those chains never came to Columbia for some reason), but never updated after their initial opening. I was more-or-less unaware that they existed until a group of friends ended up going to the Garner's Ferry location one night. Along with the standard burgers, steaks and pasta dishes, they also had a few Mexican items on the menu, and one, quesadillas was something I had never had (Mexican food was not very common at the time) and sounded interesting. In the event, I enjoyed it, but ended up with food-posioning from bad sour cream, and spent two days flat on my back (when I wasn't racing for the bathroom). I felt so low that I was unable to get up from the couch where I was lying in order to turn off the TV when one of my all-time most hated shows, The Scarecrow & Mrs. King, came on.
Needless to say, I never went back to Julies, and both locations closed sometime in the late 80s, the I-20 one after Woodhill. I don't recall anything else going into the building at Woodhill; I think it was torn down soon after Julie's closed, but I believe the building of the I-20 location did house something else before it too was demolished.
Update 30 May 2008: Added pictures of the doctor's office now on the old Julie's lot.
UPDATE 30 July 2012: I believe this building was the Julie's off I-20.